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宜宾二院胃肠外科联合泌尿外科跨学科手术:为肠癌侵犯输尿管患者争取更高生活质量  

上一条  发布日期:2026-04-22 15:11:17 更新日期:2026-05-28 09:19:08 点击次数:638   下一条


近日,宜宾市第二人民医院胃肠外科联合泌尿外科,成功为一名乙状结肠癌伴梗阻、左侧输尿管腹段受累的复杂病例实施跨学科、个体化手术治疗。术中,我院胃肠外科吴淼教授、彭孟寅医师、周世波医师团队突破术前多学科讨论(MDT)提出的需终生携带肾造瘘管的预判,在泌尿外科江永浩教授跨学科协作下通过精准切除受累输尿管并同期吻合、置入双J管,为患者争取到拔除肾造瘘管、保留正常排尿功能的机会。

宜宾二院胃肠外科联合泌尿外科跨学科手术:为肠癌侵犯输尿管患者争取更高生活质量

病例棘手:肿瘤侵犯输尿管,传统方案意味着终生带管

患者因腹痛、腹胀伴排便困难入院,经肠镜及病理检查确诊为乙状结肠癌,同时腹部增强CT提示肿瘤体积较大,造成肠腔明显狭窄、近端结肠扩张,已形成不全性肠梗阻。更为棘手的是,肿瘤向左侧腹膜后侵犯,与左侧输尿管腹段分界不清,高度怀疑输尿管受累。若不彻底处理受累输尿管,术后不仅肿瘤易残留、复发,还可能导致输尿管梗阻、肾积水,甚至肾功能丧失。

为此,我院胃肠外科启动多学科讨论,邀请泌尿外科、影像科、肿瘤科、麻醉科等专家共同研判。影像学显示肿瘤与左侧输尿管粘连紧密,长约2cm的输尿管管壁增厚、强化明显,考虑为肿瘤直接侵犯。泌尿外科专家指出,此类情况在术中往往无法单纯剥离,标准术式需切除受累输尿管段,并做肾造瘘——即通过皮肤直接穿刺肾盂建立引流通道,患者术后需终生携带肾造瘘管,定期更换管路,不仅生活质量严重下降,还面临感染、堵管、脱落等风险。然而,为了根治肿瘤、保护肾功能,术前MDT一致认为,这是最稳妥的方案。

宜宾二院胃肠外科联合泌尿外科跨学科手术:为肠癌侵犯输尿管患者争取更高生活质量

术中抉择:尽最大努力保留输尿管完整性

手术由胃肠外科吴淼教授、彭孟寅医师、周世波医师团队与泌尿外科江永浩教授团队联合实施。按预定方案,先由胃肠外科团队行乙状结肠癌根治术,规范切除肿瘤、清扫区域淋巴结,并解除肠梗阻。腹腔探查证实肿瘤已穿透肠壁,与左侧输尿管中段致密粘连,输尿管局部被肿瘤包裹,无法钝性分离。

此时,摆在手术团队面前有两个选择:一是按术前计划,切除受累输尿管,近端结扎,改行肾造瘘。二是在保证肿瘤根治的前提下,尝试切除受累输尿管段后再行端端吻合,并放置输尿管双极管(双J管)支撑引流,若吻合成功且愈合良好,患者术后可拔除造瘘管,恢复正常经膀胱排尿。但后者对手术技术、吻合口血供及张力要求极高,一旦发生吻合口漏或狭窄,可能导致严重尿性腹膜炎、肾衰竭等并发症。

经过术中商议,吴淼教授与江永浩教授一致决定:只要有一线希望保留患者自主排尿功能,就值得努力。胃肠外科团队在完整切除肿瘤的同时,精细游离并保护好输尿管两端的血供;泌尿外科江永浩教授以精准手法,完整切除了肿瘤侵犯的长约2cm输尿管段,切缘送冰冻病理提示阴性。随后,在无张力条件下用极细可吸收缝线行输尿管端端吻合,并顺利置入输尿管双极管。双极管上端位于肾盂,下端位于膀胱,起到内引流、支撑和防止狭窄的作用。术中注水试验显示吻合口无渗漏,血供良好。

团队协作:多学科融合为患者赢得拔管可能

局部晚期结直肠癌侵犯输尿管并不罕见,传统上为避免吻合口并发症,多选择肾造瘘。但随着外科技术发展和多学科协作的深入,越来越多的中心开始尝试输尿管切除重建术。本例手术的成功,关键在于术前精准评估、术中胃肠外科与泌尿外科的跨学科合作。不仅为患者切除肿瘤,还尽最大努力保留正常解剖结构和功能,正是以患者为中心的精准外科理念的体现。



Yibin Second People's Hospital Achieves Breakthrough in Complex Cancer Surgery
In a remarkable demonstration of cross-disciplinary collaboration, the Department of Gastrointestinal Surgery at Yibin Second People's Hospital, in partnership with our Urology team, has successfully performed a personalized, multi-specialty procedure on a complex case of sigmoid colon cancer with obstruction and left ureteral involvement.
During surgery, Professor Wu Miao, Dr. Peng Mengyin, and Dr. Zhou Shibo from our GI team—working alongside Professor Jiang Yonghao from Urology—achieved what pre-operative multidisciplinary discussions had deemed unlikely: rather than accepting a lifetime with a nephrostomy tube, they precisely resected the affected ureter, performed a primary anastomosis, and placed a double-J stent, giving the patient the chance to live tube-free with normal urinary function.
The Challenge: When Tumor Invades the Ureter, Standard Care Means a Lifetime of Tubes
The patient presented with abdominal pain, distension, and difficulty with bowel movements. Colonoscopy and pathology confirmed sigmoid colon cancer. Enhanced abdominal CT revealed a sizable tumor causing significant luminal narrowing and proximal colonic dilation—an incomplete bowel obstruction already in progress. More critically, the tumor had extended into the left retroperitoneum, appearing inseparable from the proximal left ureter, with strong suspicion of direct invasion.
Without addressing the ureter, the patient faced not only residual disease and recurrence risk, but also potential ureteral obstruction, hydronephrosis, and eventual loss of kidney function.
Our GI team convened a multidisciplinary discussion, bringing together experts from Urology, Radiology, Oncology, and Anesthesiology. Imaging showed dense adhesion between tumor and left ureter, with approximately 2 cm of thickened, avidly enhancing ureteral wall—consistent with tumor invasion. Our Urology specialists noted that such cases rarely allow simple dissection; standard practice would require resection of the involved segment followed by nephrostomy—creating a permanent drainage tract directly from skin to renal pelvis. This would mean lifelong tube dependence, with regular exchanges, severely diminished quality of life, and ongoing risks of infection, blockage, and dislodgement. Yet for tumor control and kidney preservation, the pre-operative MDT consensus was that this represented the safest path forward.
The Intra-Operative Decision: Fighting to Preserve Natural Function
The joint surgical team—Professors Wu Miao and Jiang Yonghao, with Drs. Peng and Zhou—proceeded with the planned approach. The GI team first performed radical sigmoid colectomy with standard lymphadenectomy, resolving the obstruction. Intra-abdominal exploration confirmed the tumor had penetrated the bowel wall and was densely adherent to the mid-left ureter, with local encasement making blunt dissection impossible.
Two options lay before the team. Option one: follow the pre-operative plan—resect the involved ureter, ligate the proximal end, and proceed with nephrostomy. Option two: attempt ureteral segmental resection with end-to-end anastomosis and double-J stent placement, preserving the possibility of post-operative tube removal and normal bladder voiding. But this alternative demanded exceptional surgical technique, optimal blood supply, and minimal tension at the anastomosis. Any leak or stricture could lead to devastating urine peritonitis or renal failure.
After intra-operative consultation, Professors Wu and Jiang reached a unanimous decision: "If there is any chance of preserving the patient's natural urinary function, it is worth every effort."
The GI team completed oncologic resection while meticulously preserving blood supply to both ureteral ends. Professor Jiang then precisely excised the 2 cm tumor-invaded segment; frozen section confirmed negative margins. Under tension-free conditions, the team performed ureteroureterostomy with fine absorbable sutures and successfully placed a double-J stent, with the proximal curl in the renal pelvis and distal curl in the bladder, providing internal drainage, structural support, and prevention of stricture. Intra-operative leak testing confirmed a watertight, well-perfused anastomosis.
Teamwork in Action: How Integrated Care Opens Doors
Locally advanced colorectal cancer with ureteral involvement is not uncommon. Traditionally, nephrostomy has been favored to avoid anastomotic complications. Yet with advancing surgical capabilities and deepening multidisciplinary collaboration, leading centers increasingly attempt ureteral resection and reconstruction.
The success of this case hinged on precise pre-operative assessment and seamless intra-operative partnership between Gastrointestinal Surgery and Urology. "Removing the tumor is only part of our mission," the team reflected. "Preserving normal anatomy and function to the greatest extent possible embodies our patient-centered philosophy of precision surgery."

At Yibin Second People's Hospital, complex cases meet comprehensive expertise. Our integrated, multidisciplinary approach means you don't have to accept compromise as the only option.
World-class surgical innovation. Personalized care. A team that fights for your quality of life.

Your journey to recovery starts here.
[本条信息由 胃肠疝外科 彭孟寅 上传]

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